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      Bulk RNA-Seq Analysis

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Discussion and Lectures
Intro to the Workshop
Schedule
What is Bioinformatics/Genomics?
Experimental Design and Cost Estimation
Closing thoughts
Data Reduction
Files and Filetypes
Prepare dataset
Preprocessing raw data
Indexing a Genome
Alignment with Star
Generating counts tables
Data analysis
Annotation from BioMart
Prepare R for data analysis
Differential Expression Analysis
Pathway Analysis
Prerequisites
CLI
R
Support
Cheat Sheets
Software and Links
Scripts
ETC
CAT website
Github page
Report Errors

All documentation for the workshop is best viewed from the github.io pages

Documentation

August 21, 2024 - August 23, 2024, 9 a.m. - 5:00 p.m Wed/Thurs, 9am to Noon Fri.

Contact - UCSF CAT Bioinformatics , catbioinformatics@ucsf.edu

Workshop Description:

This 2.5-day in-person workshop includes a half-day of introductory material, followed by two days of focused, in-depth coursework on Bulk RNA-seq. Participants will delve into Bulk RNA-Seq experiments using the command line and R, create and modify processing workflows, differential expression analysis, and diagnose and treat problematic data. A basic understanding of the command line and R is highly recommended for success in this course. We will conduct a very brief review on the first morning, but we will not be providing full instruction in basic CLI or R.

Structure:

Focus Areas:

Learning Objectives:

Prerequisites

Recommended: Basic understanding of the command line (CLI) and R. Intermediate Knowledge: Needed for maximum value from the course. Beginners: Can achieve a thorough understanding but may not be able to independently conduct an experiment.

Supplies Needed

A laptop with the command line terminal and R/Rstudio preinstalled.

Participants must have access to a computer with a reliable connection to the internet, current versions of R version 4.4.1, or at least R version >= 4.3.0 and Rstudio, and a terminal application.

We will have a dataset to use for the course, however you can bring your dataset for discussion purposes and feedback.

Recommendations for Beginners

Enroll in introductory courses in CLI and/or R courses to get the maximum out of the course.

Introductory Materials

To get the most out of this course, please complete the prerequisite material in command line and R before the course, and contact us with any questions.